Cervical Cancer

It is malignant cancer of Cervical or Cervix uteri area. Cervical cancer may present with the vaginal bleeding where symptoms may not be present until cancer in its advanced stage. Treatment consist surgery in early stage, chemotherapy and radiotherapy in its advanced stage of disease. Treatment of a high grade change can prevent development of cancer. There is wide spread use of cervical screening programs in developed countries that has reduced incidence of invasive cervical cancer by fifty percent or more. HPV (human papillomavirus infection is necessary factor in development of almost all cases of cervical cancer. Vaccine of HPV is effective against two strains of HPV that cause most cervical cancer.

 

Classification and naming of cervical carcinoma has changed many times over 20 th century. Classification system of World Health organization was descriptive of lesions, naming mild or severe dysplasia or the carcinoma in the situ. CIN (cervical intraepithelial neoplasia) was developed to place the emphsis on spectrum of the abnormality in lesions to help the standardize treatment.

 

Most recent classification is Bethesda System that divides the cervical epithelial precursor lesions in two groups is Low grade Squeamous Intraepithelial Lesion and other is its High grade.

Early stage of cervical cancer may completely asymptomatic. Bleeding, vaginal, contact bleeding or vaginal mass may indicate presence of malignancy.

 

A moderate pain during the sexual intercourse and during vaginal discharge is symptoms of the cervical cancer. In its advance disease metastases may be present in lungs, abdomen or elsewhere. Most important and a major risk factor in development of this cancer is infection with high risk strains of human papillomavirus. Link of virus cancer works by the triggering alteration in cells of cervix that can lead to develop of cervical intraepithelial neoplaisis, it can further lead to cancer. Women having more than one sexual partner have greater risk.