Multifactorial metabolic changes and complex vary lead to damage and the function impairment of organs, it is most importantly cardiovascular system in both types, and it leads to substantially increased morbidity as well as mortality in its both types. Resistance of insulin means that cells of body do not respond appropriately when the insulin in present. Insulin resistance is generally "post-receptor", unlike in type 1 diabetes.

Diabetes type 2 is unknown etiology in present, its know etiology such as secondary to some other disease trauma, known gene defects or the surgery or drugs effects, is appropriately called as "secondary diabetes".

Diabetes type 2 is chronic and progressive disease that hasn't any established cure, but it does have a well established treatment that can prevent or delay entirely formerly inevitable consequences of condition. Disease is viewed as a progressive one since poor management of blood sugar to myriad of steadily worsening complications.

It is only source of current information on glycemic state of body, as rapid and frequent changes; it is depending on exercise, food and medications with respect to exercise and diet both. National Institute for Clinical Excellence and Health , UK had released updated diabetes recommendations in year 2008. However, recent study has found that treatment strategy of lowering blood sugar in patients with cardiovascular disease poses more harm than the benefit.