Yet, there is no generally accepted cure for the fibromyalgia, and there are treatments that have been involved and demonstrated by controlled clinical trail in reducing symptoms, including, patient education, medication, behavioral interventions and exercise.

Symptoms of fibromyalgia are widespread pain, chronic and painful response to touch. Some other symptoms can also include to severe fatigue, tingling of skin, prolonged muscle spasms, muscle ache, nerve pain, weakness in limbs, bowl distribution and the chronic sleep disturbances. Many patients exercise, which may be characterized by the impaired concentration.

Some other symptoms have often attributed to the fibromyalgia, it may possibly be due to comorbid disorder include mysofascial pain also referred to chronic myosfascial pain and bowel syndrome, pain may be localized in areas such as neck, shoulders, hips, low back and in other areas of body.

There are some evidences that the genetic factors may play role in developed of fibromyalgia, there is high aggregation of fibromyalgis in the families.

Mode of inheritance is unknown currently, most probably it is polygenic, where research has demonstrated that the fibromyalgia is associated with polymorphisms, dopaminergic and catecholaminergic systems. Stress is significant precipitation factor in development of fibromyalgia. Hypothesis supposes that fourth stage of sleep is critical to function of nervous system; it is during the stage that certain processes of neurochemical in body reset. Disturbance is sleep hypothesis holds that a deep sleep is critical one to reset P substance mechanism and to prevent this out of control effect.