Headaches is associated with its specific symptoms that may warrant the urgent medical attention, severe headache, particularly sudden or sudden headache is also associated with stiff neck; it is associated with fever, accompanied or convulsions by the confusion or loss of consciousness, following below to head or is associated with eye pain or pain in ear as well.

Brain itself is not much sensitive to pain, but it is due to lacks nociptors, several areas of neck head however do have nociceptors, that can sense pain.

All headaches do not require an immediate medical attention, most response with a simple analgesia such as acetaminophen of NSAID class as acetylsalicylic acid. Over counter medications as acetaminophen are safe generally at recommended doses, recent FDA consumer control has pained out the overdose that can cause serious or fatal liver damage.

In unexplained recurrent headache, professionals of health care may recommend keekpign "headache diary" with the entries on headache type, associated symptoms and aggravating factors. It may reveal the specific patters, as association with menstruation, medication or with certain foods. In March 2007, it was reported by two separate teams of the researchers that the stimulation brain with implanted electrode appears to help ease pain of headache clusters.