Osteoporosis

It is a bone disease that leads to increasing risks of fracture, such as osteoporosis mineral density of bone is reduced, where microacrhitecture of bone is disrupted, variety and amount of non-collagenous proteins in the bones is also altered. The osteoporosis is defined by W.H.O in a woman as bone mineral density of (2.5) standard deviation below peak bone mass as measured by DXA and includes presence of fragility fracture. Often, it is most common in women, and is called postmenopausal osteoporosis; it may also develop in man and occur in any one on presence of particular hormonal disorders and some other chronic disease or result of medications.

 

Osteoporosis can also be prevented with changes in lifestyle and sometimes in medication. Change is lifestyle includes preventing exercise and falls, where medication includes calcium, bisphopsphonates and vitamin D. exercises with anabolic affect may also at same time reverse of stop osteoporosis. Underlying mechanism of osteoporosis in all cases is imbalance between bone formation and bone resorption.

 

There is a constant matrix remodeling of bone, it is up to 10% is all bone mass that can be undergoing and remodeling at any point in the time.

Amount of estrogen is needed to suppress and it is the process that is lower than normally need to stimulate uterus and the breast gland. Form of estrogen receptor appears to be most important in regulation bone turnover.

 

Calcium metabolism plays very significant role in the bone turnover, deficiency of calcium and Vitamin D and leads to impaired bone deposition. Activation of osteoclasts is regulated by the various signals of molecule, of which RANKL is one of the best studied. Itself, osteoporosis has no specific symptom, main consequence of osteoporosis occur in situations where some healthy people would not break bone normally. Typical fragility fractures occur in vertebral column, hip, rib and wrist.

 
 
 
Home | Material medico | Botiquin | Jeringas | Agujas | Guantes de vinilo | Guantes de nitrilo | Guantes de latex | Botiquines | Jeringas de insulina | Dilatadores vaginales | Termometro | Tensiometro | Bisturi | Empapadores | Gasas | Vendas | Material Sanitario | Esparadrapo | Hojas de bisturi